In the fast-evolving cannabis industry, manufacturers have long grappled with challenges related to consistency and bioavailability in products like gummies, confections, beverages, lozenges, and edibles. However, groundbreaking scientific research and pharmacokinetic testing now reveal that high-quality nanoemulsions could hold the key to unlocking faster, more effective, and consistent uptake of essential ingredients, especially the hard-to-absorb, fat-soluble cannabinoids.
Cannabis is a natural product with considerable variability, necessitating refining processes for successful integration into food and beverage items with precise controls. Nanoemulsions significantly improve bioavailability and onset due to their small droplet size, allowing the body to break down and absorb the particles more efficiently.
In simple terms, nanoemulsions with 20-nanometer droplets, as opposed to larger 120-nanometer droplets, become more digestible and readily metabolized, leading to enhanced performance.
There are three primary benefits to incorporating nanoemulsions into cannabis products:
Assessing the efficacy of cannabinoids and terpenes in edibles requires precision. One effective method to measure performance is through human uptake studies, where subjects consume the product, and their blood is drawn over time. Mass spectrometers then measure the concentration of cannabinoids in the blood, providing objective data on the product’s effectiveness.
Another option is Caco-2 GI permeability assays, which determine how quickly materials migrate between two liquids separated by a layer of cells. While useful, these tests are relative and do not provide in-depth insights into timing and long-term effects like blood draw tests do.
Pharmacokinetic testing data has unveiled that high-quality nanoemulsions offer outstanding uptake, faster effects, and more efficient bioavailability, providing manufacturers with a substantial competitive advantage in a crowded market. Moreover, delivering a consistent consumer experience builds trust and encourages repeat purchases, making nanoemulsion technology a game-changer in the cannabis industry.
Manufacturers keen on staying ahead of the curve should embrace this innovative technology, leveraging nanoemulsions to revolutionize the cannabis experience and deliver products that consistently meet consumer expectations and desired outcomes.